Etihad Stadium - Champions League
Manchester City have a three goal deficit to overturn, as they host a Liverpool side that are in fine form, despite drawing at the weekend. A loss for City on Tuesday would be their third in a row, whereas the Reds have gone four unbeaten coming into the fixture.
Liverpool pulled off the shock of the Champions League knock-out stages, not only beating City, but keeping a clean sheet against them. Jurgen Klopp's side scored all three goals before half-time, thanks to Mohammed Salah, Sadio Mane and a thunderbolt from Alex Oxlade-Chamberlain. The second half was dominated by City, with Klopp furious after the game that his side let Pep Guardiola's side put them under so much pressure.
Benjamin Mendy is the only injured player for Manchester City, with Guardiola dropping the likes of Sergio Aguero and Kevin De Bruyne from the starting XI on Saturday. The manager will likely keep faith in his stars, despite their poor performance at Anfield.
Klopp has a far more extensive injury list, not helped by Jordan Henderson's suspension after picking up a yellow card against City. In addition to the captain, fellow midfielders Adam Lallana and Emre Can are both out injured, meaning a start in the middle of the park is likely for James Milner. Joel Matip has been sidelined for the remainder of the season, whilst Joseph Gomez's injury on international duty leaves the manager short on defensive options.
Manchester City v Liverpool Preview and Predictions
Manchester City will go into this game with a point to prove, having wasted a two goal lead to loose at home to Manchester United. Guardiola would have liked nothing more than to have wrapped up the Premier League on Saturday, and a moral improving win over United would have been an added bonus.
As it is, City have gone two games without a win, and have had their defensive frailties shown, although they are still pretty much guaranteed champions come the end of the season. City can find solace in their last home game against Liverpool, which they won by five goals to nil, with two braces from Gabriel Jesus and Leroy Sane and a goal from Aguero. The same scoreline would see Guardola's side qualify with goals to spare, and the coach may risk fielding two strikers again in a bid to turn it around.
Jurgen Klopp will be far more worried than usual for a manager three goals to the good. As Liverpool fans know very well, a three goal lead is not a guaranteed victory, and the squad is missing their captain in the centre of the park. The Reds have been phenomenal going forward this season, but have been comparatively poor in defence, relying on outscoring their opponents rather than containing them.
The question remains whether Klopp is willing to risk a change of tactics in order to shut up shop against City, or if he will stick to his guns and hope Mo Salah can inspire his team to victory.
Sergio Aguero to score anytime at 4/5
The Argentinian has a habit of scoring important goals and should get the start having missed out against United.
Over 3.5 goals scored at 5/6
City need 3 to progress, and if they push forward they will open up space for Liverpool's tricky wingers.